{"id":3538,"date":"2025-05-20T08:38:37","date_gmt":"2025-05-20T06:38:37","guid":{"rendered":"https:\/\/remeds.org\/?p=3538"},"modified":"2025-09-10T08:52:55","modified_gmt":"2025-09-10T06:52:55","slug":"early-results-hero-trial","status":"publish","type":"post","link":"https:\/\/remeds.org\/tr\/2025\/05\/20\/early-results-hero-trial\/","title":{"rendered":"MDS i\u00e7in HERO Denemesi'nden umut vadeden ilk sonu\u00e7lar"},"content":{"rendered":"<p>Bu y\u0131l\u0131n ba\u015flar\u0131nda Alvin Luk, MECP2 Duplikasyon Sendromu i\u00e7in HERO klinik denemesini g\u00fcncellemek \u00fczere Kopenhag'daki CRISPR T\u0131p Konferans\u0131'na kat\u0131ld\u0131. Alvin'in sunumu YouTube'da toplulu\u011fun izlemesi i\u00e7in mevcut.<\/p>\n\n\n\n<p>Bu videoda, Huidagene'in deneysel CRISPR-Cas13 tedavisini \u00f6\u011freneceksiniz, <strong>HG204<\/strong>, ve incelenen ilac\u0131 ald\u0131ktan \u00fc\u00e7 ay sonra tedavi edilen ilk \u00e7ocu\u011fun ilerlemesini g\u00f6r\u00fcn. Atla <strong>dakika 26:00<\/strong> hastan\u0131n video g\u00f6r\u00fcnt\u00fcleri i\u00e7in.<\/p>\n\n\n\n<p>Bu erken sonu\u00e7lar \u00e7ok te\u015fvik edici ve MeCP2 protein seviyelerinin restore edilmesinin MDS ile m\u00fccadelede umut verici bir strateji olabilece\u011fini daha da g\u00f6stermektedir.<\/p>\n\n\n\n<p>\u00c7in'deki bu denemede HG204 ile ikinci bir \u00e7ocuk daha tedavi edildi ve s\u0131rayla alt\u0131 hastan\u0131n kat\u0131lmas\u0131 bekleniyor.<\/p>\n\n\n\n<p><a href=\"https:\/\/dupmecp2.eu\/recruitement-hero\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"560\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png\" alt=\"\" class=\"wp-image-3539\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-300x164.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-768x420.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1536x841.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025.png 1842w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3542\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png\" alt=\"\" class=\"wp-image-3542\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-300x168.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1536x862.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"576\" data-id=\"3544\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png\" alt=\"\" class=\"wp-image-3544\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-768x432.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1536x864.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4.png 2008w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3541\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png\" alt=\"\" class=\"wp-image-3541\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1536x863.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/figure>\n\n\n\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\" data-type=\"link\" data-id=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\">Videoya<\/a><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Earlier this year, Alvin Luk attended the CRISPR Medicine Conference in Copenhagen to provide an update on the HERO clinical trial for MECP2 Duplication Syndrome. Alvin\u2019s presentation is available for the community to watch on YouTube. In this video, you\u2019ll learn about Huidagene\u2019s experimental CRISPR-Cas13 therapy, HG204, and see the progress in the first treated [&hellip;]<\/p>\n","protected":false},"author":114,"featured_media":3553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[12,10,9],"tags":[],"class_list":["post-3538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crispr","category-cure","category-research"],"_links":{"self":[{"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/posts\/3538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/comments?post=3538"}],"version-history":[{"count":10,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/posts\/3538\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/posts\/3538\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/media\/3553"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/media?parent=3538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/categories?post=3538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/tr\/wp-json\/wp\/v2\/tags?post=3538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}