{"id":3538,"date":"2025-05-20T08:38:37","date_gmt":"2025-05-20T06:38:37","guid":{"rendered":"https:\/\/remeds.org\/?p=3538"},"modified":"2025-09-10T08:52:55","modified_gmt":"2025-09-10T06:52:55","slug":"early-results-hero-trial","status":"publish","type":"post","link":"https:\/\/remeds.org\/ja\/2025\/05\/20\/early-results-hero-trial\/","title":{"rendered":"MDS\u3092\u5bfe\u8c61\u3068\u3057\u305fHERO\u8a66\u9a13\u306e\u6709\u671b\u306a\u521d\u671f\u7d50\u679c"},"content":{"rendered":"

\u4eca\u5e74\u521d\u3081\u3001\u30a2\u30eb\u30d3\u30f3\u30fb\u30eb\u30fc\u30af\u306f\u30b3\u30da\u30f3\u30cf\u30fc\u30b2\u30f3\u3067\u958b\u50ac\u3055\u308c\u305fCRISPR Medicine Conference\u306b\u51fa\u5e2d\u3057\u3001MECP2\u91cd\u8907\u75c7\u5019\u7fa4\u306eHERO\u81e8\u5e8a\u8a66\u9a13\u306e\u9032\u6357\u72b6\u6cc1\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002\u30a2\u30eb\u30d3\u30f3\u306e\u30d7\u30ec\u30bc\u30f3\u30c6\u30fc\u30b7\u30e7\u30f3\u306fYouTube\u3067\u8996\u8074\u3067\u304d\u307e\u3059\u3002.<\/p>\n\n\n\n

\u3053\u306e\u30d3\u30c7\u30aa\u3067\u306f\u3001Huidagene\u793e\u306e\u5b9f\u9a13\u7684\u306aCRISPR-Cas13\u7642\u6cd5\u306b\u3064\u3044\u3066\u5b66\u3073\u307e\u3059\u3002, \uff28\uff27\uff12\uff10\uff14<\/strong>, \u3001\u305d\u3057\u3066\u6cbb\u9a13\u85ac\u6295\u4e0e\u304b\u30893\u30f6\u6708\u5f8c\u306e\u6700\u521d\u306e\u6cbb\u7642\u3092\u53d7\u3051\u305f\u5b50\u4f9b\u306e\u9032\u6357\u72b6\u6cc1\u3092\u898b\u3066\u304f\u3060\u3055\u3044\u3002\u30b9\u30ad\u30c3\u30d7 26\u520600\u79d2<\/strong> \u60a3\u8005\u306e\u30d3\u30c7\u30aa\u6620\u50cf\u306e\u305f\u3081.<\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u521d\u671f\u306e\u7d50\u679c\u306f\u975e\u5e38\u306b\u6709\u671b\u3067\u3042\u308a\u3001MeCP2\u30bf\u30f3\u30d1\u30af\u8cea\u30ec\u30d9\u30eb\u3092\u56de\u5fa9\u3055\u305b\u308b\u3053\u3068\u304cMDS\u306b\u53d6\u308a\u7d44\u3080\u305f\u3081\u306e\u6709\u671b\u306a\u6226\u7565\u3068\u306a\u308a\u3046\u308b\u3053\u3068\u3092\u3055\u3089\u306b\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002.<\/p>\n\n\n\n

\u4e2d\u56fd\u3067\u306f\u3001\u3059\u3067\u306b2\u4eba\u76ee\u306e\u5b50\u4f9b\u304cHG204\u306b\u3088\u308b\u6cbb\u7642\u3092\u53d7\u3051\u3066\u304a\u308a\u3001\u672c\u6cbb\u9a13\u306b\u306f\u6700\u9ad86\u4eba\u306e\u60a3\u8005\u3092\u9806\u6b21\u767b\u9332\u3059\u308b\u4e88\u5b9a\u3067\u3059\u3002.<\/p>\n\n\n\n

<\/a><\/p>\n\n\n\n

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\"\"<\/figure>\n\n\n\n
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\"\"<\/figure>\n<\/figure>\n\n\n\n

\u30d3\u30c7\u30aa\u3078<\/a><\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Earlier this year, Alvin Luk attended the CRISPR Medicine Conference in Copenhagen to provide an update on the HERO clinical trial for MECP2 Duplication Syndrome. Alvin\u2019s presentation is available for the community to watch on YouTube. In this video, you\u2019ll learn about Huidagene\u2019s experimental CRISPR-Cas13 therapy, HG204, and see the progress in the first treated child, three months after receiving the investigational drug. Skip to minute 26:00 for video footage of the patient. These early results are very encouraging and further suggest that restoring MeCP2 protein levels could be a promising strategy to tackle MDS. A second child has already been treated with HG204, and up to six patients are […]<\/p>\n","protected":false},"author":114,"featured_media":3553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[12,10,9],"tags":[],"class_list":["post-3538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crispr","category-cure","category-research"],"_links":{"self":[{"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/posts\/3538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/comments?post=3538"}],"version-history":[{"count":10,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/posts\/3538\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/posts\/3538\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/media\/3553"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/media?parent=3538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/categories?post=3538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/ja\/wp-json\/wp\/v2\/tags?post=3538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}