{"id":3538,"date":"2025-05-20T08:38:37","date_gmt":"2025-05-20T06:38:37","guid":{"rendered":"https:\/\/remeds.org\/?p=3538"},"modified":"2025-09-10T08:52:55","modified_gmt":"2025-09-10T06:52:55","slug":"early-results-hero-trial","status":"publish","type":"post","link":"https:\/\/remeds.org\/hr\/2025\/05\/20\/early-results-hero-trial\/","title":{"rendered":"Ohrabruju\u0107i rani rezultati HERO ispitivanja za MDS"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Ranije ove godine, Alvin Luk prisustvovao je CRISPR Medicine Conference u Kopenhagenu kako bi pru\u017eio a\u017eurirani prikaz klini\u010dkog ispitivanja HERO za MECP2 Duplication Syndrome. Alvinova prezentacija dostupna je zajednici za gledanje na YouTubeu.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">U ovom videozapisu nau\u010dit \u0107ete o Huidageneovoj eksperimentalnoj CRISPR-Cas13 terapiji, <strong>HG204<\/strong>, i vidjeti napredak kod prvog djeteta koje je primilo istra\u017eiva\u010dki lijek, tri mjeseca nakon primanja. Presko\u010di na <strong>minuta 26:00<\/strong> za video snimku pacijenta.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ovi rani rezultati su vrlo poticajni i dodatno sugeriraju da bi obnavljanje razine MeCP2 proteina moglo biti obe\u0107avaju\u0107a strategija za lije\u010denje MDS-a.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Drugo dijete je ve\u0107 lije\u010deno lijekom HG204, a o\u010dekuje se da \u0107e u ovom ispitivanju u Kini biti uklju\u010deno do \u0161est pacijenata sekvencijalno.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/dupmecp2.eu\/recruitement-hero\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"560\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png\" alt=\"\" class=\"wp-image-3539\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-300x164.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-768x420.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1536x841.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025.png 1842w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3542\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png\" alt=\"\" class=\"wp-image-3542\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-300x168.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1536x862.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"576\" data-id=\"3544\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png\" alt=\"\" class=\"wp-image-3544\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-768x432.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1536x864.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4.png 2008w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3541\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png\" alt=\"\" class=\"wp-image-3541\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1536x863.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\" data-type=\"link\" data-id=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\">Na video<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Earlier this year, Alvin Luk attended the CRISPR Medicine Conference in Copenhagen to provide an update on the HERO clinical trial for MECP2 Duplication Syndrome. Alvin\u2019s presentation is available for the community to watch on YouTube. In this video, you\u2019ll learn about Huidagene\u2019s experimental CRISPR-Cas13 therapy, HG204, and see the progress in the first treated [&hellip;]<\/p>\n","protected":false},"author":114,"featured_media":3553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[12,10,9],"tags":[],"class_list":["post-3538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crispr","category-cure","category-research"],"_links":{"self":[{"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/posts\/3538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/comments?post=3538"}],"version-history":[{"count":10,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/posts\/3538\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/posts\/3538\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/media\/3553"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/media?parent=3538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/categories?post=3538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/hr\/wp-json\/wp\/v2\/tags?post=3538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}