{"id":3538,"date":"2025-05-20T08:38:37","date_gmt":"2025-05-20T06:38:37","guid":{"rendered":"https:\/\/remeds.org\/?p=3538"},"modified":"2025-09-10T08:52:55","modified_gmt":"2025-09-10T06:52:55","slug":"early-results-hero-trial","status":"publish","type":"post","link":"https:\/\/remeds.org\/fr\/2025\/05\/20\/early-results-hero-trial\/","title":{"rendered":"R\u00e9sultats pr\u00e9coces prometteurs de l'essai HERO pour le SMD"},"content":{"rendered":"

Plus t\u00f4t cette ann\u00e9e, Alvin Luk a assist\u00e9 \u00e0 la Conf\u00e9rence CRISPR Medicine \u00e0 Copenhague pour pr\u00e9senter une mise \u00e0 jour sur l'essai clinique HERO pour le syndrome de duplication MECP2. La pr\u00e9sentation d'Alvin est disponible en ligne sur YouTube pour que la communaut\u00e9 puisse la regarder.<\/p>\n\n\n\n

Dans cette vid\u00e9o, vous d\u00e9couvrirez la th\u00e9rapie CRISPR-Cas13 exp\u00e9rimentale de Huidagene, HG204<\/strong>, et constater les progr\u00e8s chez le premier enfant trait\u00e9, trois mois apr\u00e8s avoir re\u00e7u le m\u00e9dicament exp\u00e9rimental. Passer \u00e0 minute 26:00<\/strong> pour des s\u00e9quences vid\u00e9o du patient.<\/p>\n\n\n\n

Ces premiers r\u00e9sultats sont tr\u00e8s encourageants et sugg\u00e8rent encore davantage que la restauration des niveaux de prot\u00e9ines MeCP2 pourrait \u00eatre une strat\u00e9gie prometteuse pour lutter contre le MDS.<\/p>\n\n\n\n

Un deuxi\u00e8me enfant a d\u00e9j\u00e0 \u00e9t\u00e9 trait\u00e9 avec le HG204, et jusqu'\u00e0 six patients devraient \u00eatre inclus s\u00e9quentiellement dans cet essai en Chine.<\/p>\n\n\n\n

<\/a><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n<\/figure>\n\n\n\n

\u00c0 la vid\u00e9o<\/a><\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Earlier this year, Alvin Luk attended the CRISPR Medicine Conference in Copenhagen to provide an update on the HERO clinical trial for MECP2 Duplication Syndrome. Alvin\u2019s presentation is available for the community to watch on YouTube. In this video, you\u2019ll learn about Huidagene\u2019s experimental CRISPR-Cas13 therapy, HG204, and see the progress in the first treated […]<\/p>\n","protected":false},"author":114,"featured_media":3553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[12,10,9],"tags":[],"class_list":["post-3538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crispr","category-cure","category-research"],"_links":{"self":[{"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/posts\/3538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/comments?post=3538"}],"version-history":[{"count":10,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/posts\/3538\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/posts\/3538\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/media\/3553"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/media?parent=3538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/categories?post=3538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/fr\/wp-json\/wp\/v2\/tags?post=3538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}