{"id":3562,"date":"2025-06-02T08:54:11","date_gmt":"2025-06-02T06:54:11","guid":{"rendered":"https:\/\/remeds.org\/?p=3562"},"modified":"2025-11-14T09:26:07","modified_gmt":"2025-11-14T08:26:07","slug":"umass-licenses-sirna-mecp2-duplication-syndrome","status":"publish","type":"post","link":"https:\/\/remeds.org\/el\/2025\/06\/02\/umass-licenses-sirna-mecp2-duplication-syndrome\/","title":{"rendered":"\u039d\u03ad\u03bf \u03b2\u03ae\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b1 \u03b5\u03bc\u03c0\u03c1\u03cc\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2: \u03a4\u03bf UMass Chan \u03b1\u03b4\u03b5\u03b9\u03bf\u03b4\u03bf\u03c4\u03b5\u03af \u03c4\u03b7\u03bd \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 siRNA \u00a0"},"content":{"rendered":"<p>\u0397 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03a3\u03c7\u03bf\u03bb\u03ae UMass Chan \u03ad\u03c7\u03b5\u03b9 \u03c0\u03b1\u03c1\u03b1\u03c7\u03c9\u03c1\u03ae\u03c3\u03b5\u03b9 \u03ac\u03b4\u03b5\u03b9\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b7\u03c2 \u03bc\u03b9\u03b1\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 siRNA \u03c3\u03c4\u03b7\u03bd M2DS, \u03bc\u03b9\u03b1 \u03bd\u03b5\u03bf\u03c3\u03cd\u03c3\u03c4\u03b1\u03c4\u03b7 \u03b5\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c6\u03bf\u03c3\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03ce\u03b8\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c9\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03a3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u0394\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd MECP2. \u0391\u03c5\u03c4\u03cc \u03c3\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03bf\u03c4\u03b5\u03af \u03ad\u03bd\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03b2\u03ae\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1.<a href=\"https:\/\/dupmecp2.eu\/recruitement-hero\/\"><\/a><\/p>\n\n\n\n<p>\u0397 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03b1\u03bd\u03b1\u03c0\u03c4\u03cd\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03c4\u03b7\u03c2 \u0394\u03c1. Khvorova, \u03bc\u03b5 \u03b5\u03c0\u03b9\u03ba\u03b5\u03c6\u03b1\u03bb\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03ad\u03c1\u03b3\u03bf\u03c5 \u03c4\u03bf\u03bd Vignesh Hariharan. \u0397 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03ad\u03b3\u03b9\u03bd\u03b5 \u03c7\u03ac\u03c1\u03b7 \u03c3\u03c4\u03b7 \u03c7\u03c1\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd Cure MDS \u03ba\u03b1\u03b9 \u03c4\u03bf Rett Syndrome Research Trust. \u0391\u03c5\u03c4\u03cc \u03c4\u03bf siRNA \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03c3\u03c4\u03bf\u03c7\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03b9\u03ba\u03bf\u03b4\u03bf\u03bc\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03b1\u03b3\u03b3\u03b5\u03bb\u03b9\u03b1\u03c6\u03cc\u03c1\u03bf RNA \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MeCP2. <\/p>\n\n\n\n<p>\u03a3\u03b5 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03c3\u03b5 \u03c0\u03bf\u03bd\u03c4\u03af\u03ba\u03b9\u03b1, \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7 \u03ad\u03c6\u03c4\u03b1\u03c3\u03b5 \u03c3\u03c4\u03bf\u03bd \u03b5\u03b3\u03ba\u03ad\u03c6\u03b1\u03bb\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03bd\u03c9\u03c4\u03b9\u03b1\u03af\u03bf \u03bc\u03c5\u03b5\u03bb\u03cc \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03bc\u03cc\u03bd\u03bf \u03bc\u03af\u03b1 \u03ae \u03b4\u03cd\u03bf \u03c6\u03bf\u03c1\u03ad\u03c2 \u03b5\u03c4\u03b7\u03c3\u03af\u03c9\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7. \u039c\u03b5 \u03c4\u03b7\u03bd \u03b1\u03b4\u03b5\u03b9\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7 \u03b1\u03c5\u03c4\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03c3\u03c4\u03b7\u03bd M2DS, \u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b5\u03b9\u03c3\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03c4\u03ce\u03c1\u03b1 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03cc\u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bb\u03ac\u03b2\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c7\u03c9\u03c1\u03ae\u03c3\u03b5\u03b9 \u03c0\u03c1\u03bf\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03c3\u03b5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2. <\/p>\n\n\n\n<p>\u0395\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c3\u03c5\u03bd\u03b5\u03c7\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd Ionis \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd HuidaGene, \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03bf\u03c1\u03cc\u03c3\u03b7\u03bc\u03bf \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ad\u03c3\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c3\u03c4\u03bf\u03bd \u03b1\u03b3\u03c9\u03b3\u03cc \u03c0\u03b9\u03b8\u03b1\u03bd\u03ce\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03b9\u03ce\u03bd \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03ae\u03bd \u03c4\u03b7 \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03cd\u03c0\u03bb\u03bf\u03ba\u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><a href=\"https:\/\/bridge.umassmed.edu\/s\/news\/news-article\/umass-chan-licenses-sirna-therapeutics-for-mecp2-duplication-syndrome-MCMWKNCJYQ25CQHF5YITTOM757HU\">\u0394\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03b4\u03b5\u03bb\u03c4\u03af\u03bf \u03c4\u03cd\u03c0\u03bf\u03c5<\/a><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>UMass Chan Medical School has licensed a promising siRNA-based technology to M2DS, a startup company dedicated to advancing the technology as a treatment for MECP2 Duplication Syndrome. This marks a major step forward in translating cutting-edge research into clinical reality. The technology was developed in the lab of Dr. Khvorova, with the project led by [&hellip;]<\/p>\n","protected":false},"author":114,"featured_media":3563,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[9,24],"tags":[],"class_list":["post-3562","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","category-sirna"],"_links":{"self":[{"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/posts\/3562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/comments?post=3562"}],"version-history":[{"count":3,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/posts\/3562\/revisions"}],"predecessor-version":[{"id":3567,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/posts\/3562\/revisions\/3567"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/media\/3563"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/media?parent=3562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/categories?post=3562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/el\/wp-json\/wp\/v2\/tags?post=3562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}