{"id":3538,"date":"2025-05-20T08:38:37","date_gmt":"2025-05-20T06:38:37","guid":{"rendered":"https:\/\/remeds.org\/?p=3538"},"modified":"2025-09-10T08:52:55","modified_gmt":"2025-09-10T06:52:55","slug":"early-results-hero-trial","status":"publish","type":"post","link":"https:\/\/remeds.org\/de\/2025\/05\/20\/early-results-hero-trial\/","title":{"rendered":"Vielversprechende erste Ergebnisse aus der HERO-Studie f\u00fcr MDS"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Anfang dieses Jahres besuchte Alvin Luk die CRISPR Medicine Conference in Kopenhagen, um ein Update zur HERO-Studie f\u00fcr das MECP2-Duplikationssyndrom zu geben. Alvins Pr\u00e4sentation kann von der Community auf YouTube angesehen werden.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In diesem Video lernen Sie die experimentelle CRISPR-Cas13-Therapie von Huidagene kennen., <strong>HG204<\/strong>, und den Fortschritt des ersten behandelten Kindes drei Monate nach Erhalt des experimentellen Medikaments zu sehen. \u00dcberspringen <strong>Minute 26:00<\/strong> f\u00fcr Videomaterial des Patienten.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Diese fr\u00fchen Ergebnisse sind sehr ermutigend und deuten ferner darauf hin, dass die Wiederherstellung des MeCP2-Proteinspiegels eine vielversprechende Strategie zur Bek\u00e4mpfung von MDS sein k\u00f6nnte.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ein zweites Kind wurde bereits mit HG204 behandelt, und es wird erwartet, dass bis zu sechs Patienten nacheinander in diese Studie in China aufgenommen werden.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/dupmecp2.eu\/recruitement-hero\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"560\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png\" alt=\"\" class=\"wp-image-3539\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1024x560.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-300x164.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-768x420.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1536x841.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025.png 1842w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3542\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png\" alt=\"\" class=\"wp-image-3542\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-300x168.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-1536x862.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-1.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"576\" data-id=\"3544\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png\" alt=\"\" class=\"wp-image-3544\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1024x576.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-768x432.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-1536x864.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-4.png 2008w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"575\" data-id=\"3541\" src=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png\" alt=\"\" class=\"wp-image-3541\" srcset=\"https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1024x575.png 1024w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-300x169.png 300w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-768x431.png 768w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-1536x863.png 1536w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5-18x10.png 18w, https:\/\/remeds.org\/wp-content\/uploads\/2025\/09\/HERO-CRISPR-conference-2025-5.png 2006w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\" data-type=\"link\" data-id=\"https:\/\/www.youtube.com\/watch?v=uVFNm1UWQv8\">Zum Video<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Earlier this year, Alvin Luk attended the CRISPR Medicine Conference in Copenhagen to provide an update on the HERO clinical trial for MECP2 Duplication Syndrome. Alvin\u2019s presentation is available for the community to watch on YouTube. In this video, you\u2019ll learn about Huidagene\u2019s experimental CRISPR-Cas13 therapy, HG204, and see the progress in the first treated [&hellip;]<\/p>\n","protected":false},"author":114,"featured_media":3553,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jf_save_progress":"","footnotes":""},"categories":[12,10,9],"tags":[],"class_list":["post-3538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crispr","category-cure","category-research"],"_links":{"self":[{"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/posts\/3538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/comments?post=3538"}],"version-history":[{"count":10,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/posts\/3538\/revisions"}],"predecessor-version":[{"id":3559,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/posts\/3538\/revisions\/3559"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/media\/3553"}],"wp:attachment":[{"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/media?parent=3538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/categories?post=3538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/remeds.org\/de\/wp-json\/wp\/v2\/tags?post=3538"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}